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Hyperventilation-induced alkalo-sis, which anecdotally appeared to reduce theneed for extracorporeal membrane oxygenation(ECMO) in infants with PPHN (Walsh-Sukyset al. The disorderis caused by a mutation in the gene encoding the receptorfor the peroxisome targeting signal that does not recognizethe signal Ser-Lys-Leu at the carboxy-terminus of enzymesdirected to peroxisomes

The disorderis caused by a mutation in the gene encoding the receptorfor the peroxisome targeting signal that does not recognizethe signal Ser-Lys-Leu at the carboxy-terminus of enzymesdirected to peroxisomes.

Sonication culture aswell as cultures from five out of six intraoperative biopsies showed growth of the sameCNS.

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